Title :
Free energy periodicity in E.coli
Author :
Rosnick, David I. ; Bitzer, Donald L. ; Vouk, Mladen A. ; May, Elebeoba E.
Author_Institution :
Dept. of Comput. Sci., North Carolina State Univ., Raleigh, NC, USA
Abstract :
It has been seen that sequences upstream from coding regions tend to possess significant complementarity to the exposed part of the 16S rRNA in E.coli. While upstream binding between the Shine-Dalgarno sequence and the mRNA may be a necessary condition for translation, it appears to be insufficient. By computing the free energy binding within the coding sequence, it is suggested that the 16S has a continuing role through elongation of translation as well
Keywords :
cellular biophysics; free energy; microorganisms; 16S rRNA; E.coli; Shine-Dalgarno sequence; coding regions; coding sequence; free energy periodicity; translation elongation; upstream binding; Bioinformatics; Computer science; DNA computing; Data analysis; Data visualization; Databases; Genomics; Sequences; Signal analysis; Sun;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.804382
