Title :
Development of laser fluorimetric detector for high-performance liquid chromatography
Author :
Samoilova, E.S. ; Mashalkin, Yu.P. ; Fedorov, V.I. ; Cherkasova, O.P.
Author_Institution :
Russian Acad. of Sci., Inst. of Laser Phys., Novosibirsk
Abstract :
Highly sensitive laser fluorescent detectors are required for high-performance liquid chromatography (HPLC). In a series of cases using laser excitation sources allows one to solve the problem of reaching low limits of detection even for the agents with low quantum yields of fluorescence. The primary task in designing laser detector lies in the choice of laser source based on the following parameters: radiation wave length, output power, pulsed continuous operation conditions, stability, noise stability, dimension and cost
Keywords :
chromatography; measurement by laser beam; spectrochemical analysis; laser excitation; laser fluorimetric detector; liquid chromatography; quantum yield; Costs; Fluorescence; Laser excitation; Laser noise; Laser stability; Optical design; Optical pulses; Power generation; Power lasers; Radiation detectors;
Conference_Titel :
Modern Techniques and Technologies, 2003. MTT 2003. Proceedings of the 9th International Scientific and Practical Conference of Students, Post-graduates and Young Scientists
Conference_Location :
Tomsk
Print_ISBN :
0-7803-7669-2
DOI :
10.1109/SPCMTT.2003.1438209
