• DocumentCode
    3317100
  • Title

    Notice of Retraction
    Small-World Network Properties of Protein Complexes: Node Centrality and Community Structure

  • Author

    Gouchol Pok ; Ho Sun Shon ; Kyung-Ah Kim ; Ken Ho Ryu

  • Author_Institution
    Dept. of Comput. Sci., Yanbian Univ. of Sci. & Technol., Yanji, China
  • fYear
    2011
  • fDate
    10-12 May 2011
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    Notice of Retraction

    After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.

    We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

    The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.

    Recently the biological networks have been examined by borrowing the techniques and concepts mainly developed for social networks. In particular protein complexes are found to show small-world behavior. In this study, we show that the set of accessible surface area for amino acids are inversely correlated with the values of vertex betweenness. Under this global trend, specificity for the hot spots in protein interface are further studied. We also show that amino acid residue communities, which are constructed by the iterative elimination of high edge betweenness values in the descending order, are formed around the hot spot residues located in the protein interface area. Experiments with real proteins with known structure verify the small-world behavior of the protein complexes.
  • Keywords
    iterative methods; molecular biophysics; proteins; amino acids; community structure; node centrality; protein complexes; small-world network properties; Amino acids; Communities; Correlation; Image edge detection; Protein engineering; Proteins; Solvents;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
  • Conference_Location
    Wuhan
  • ISSN
    2151-7614
  • Print_ISBN
    978-1-4244-5088-6
  • Type

    conf

  • DOI
    10.1109/icbbe.2011.5779978
  • Filename
    5779978