Notice of RetractionSmall-World Network Properties of Protein Complexes: Node Centrality and Community Structure

Notice of Retraction

After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.

We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.

Recently the biological networks have been examined by borrowing the techniques and concepts mainly developed for social networks. In particular protein complexes are found to show small-world behavior. In this study, we show that the set of accessible surface area for amino acids are inversely correlated with the values of vertex betweenness. Under this global trend, specificity for the hot spots in protein interface are further studied. We also show that amino acid residue communities, which are constructed by the iterative elimination of high edge betweenness values in the descending order, are formed around the hot spot residues located in the protein interface area. Experiments with real proteins with known structure verify the small-world behavior of the protein complexes.