DocumentCode
3317453
Title
Notice of Retraction
A Novel Strategy for Identification of Biosynthesis Pathway of Emodin in Aspergillus ochraceus by Stable-Isotope Labeling and HPLC-ESI/APCI-MS
Author
Qin Pei ; Lv Ping ; Li Yuan Zhen ; Tang Yi Wei ; Wang Yu
Author_Institution
Coll. of Food Eng. & Biotechnol., Tianjin Univ. of Sci. & Technol., Tianjin, China
fYear
2011
fDate
10-12 May 2011
Firstpage
1
Lastpage
3
Abstract
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
In order to identify the biosynthesis pathway of emodin in Aspergillus ochraceus, a series of molecular weight margins between the C13 labeled and the C12 labeled intermediates in the biosynthesis pathway of emodin was scanned by stable-isotope labeling and High pressure Tiquid Chromatography electrospray ionization or atmosphere pressure chemical ionization Mass spectrometry (HPTC-ESI/APCI-MS) and analyzed in the mode of dynamic statistics. It was confirm that emodin was biosynthesized by ployketide pathways, two carbon units derived from acetyl coenzyme A were not only precursors of emodin but also elongation units and there were 7 circulations in the process of emodin biosynthesis.
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
In order to identify the biosynthesis pathway of emodin in Aspergillus ochraceus, a series of molecular weight margins between the C13 labeled and the C12 labeled intermediates in the biosynthesis pathway of emodin was scanned by stable-isotope labeling and High pressure Tiquid Chromatography electrospray ionization or atmosphere pressure chemical ionization Mass spectrometry (HPTC-ESI/APCI-MS) and analyzed in the mode of dynamic statistics. It was confirm that emodin was biosynthesized by ployketide pathways, two carbon units derived from acetyl coenzyme A were not only precursors of emodin but also elongation units and there were 7 circulations in the process of emodin biosynthesis.
Keywords
biotechnology; chromatography; elongation; ionisation; mass spectroscopy; microorganisms; APCI-MS; Aspergillus ochraceus; HPLC-ESI; atmosphere pressure chemical ionization; biosynthesis identification; dynamic statistics; electrospray ionization; elongation; emodin pathway; emodin precursors; high pressure liquid chromatography; mass spectrometry; molecular weight margins; stable-isotope labeling; Carbon; Impurities; Ionization; Labeling; Production; Temperature; Temperature control;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location
Wuhan
ISSN
2151-7614
Print_ISBN
978-1-4244-5088-6
Type
conf
DOI
10.1109/icbbe.2011.5779998
Filename
5779998
Link To Document