Notice of RetractionA Novel Strategy for Identification of Biosynthesis Pathway of Emodin in Aspergillus ochraceus by Stable-Isotope Labeling and HPLC-ESI/APCI-MS

Notice of Retraction

After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.

We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.

In order to identify the biosynthesis pathway of emodin in Aspergillus ochraceus, a series of molecular weight margins between the C13 labeled and the C12 labeled intermediates in the biosynthesis pathway of emodin was scanned by stable-isotope labeling and High pressure Tiquid Chromatography electrospray ionization or atmosphere pressure chemical ionization Mass spectrometry (HPTC-ESI/APCI-MS) and analyzed in the mode of dynamic statistics. It was confirm that emodin was biosynthesized by ployketide pathways, two carbon units derived from acetyl coenzyme A were not only precursors of emodin but also elongation units and there were 7 circulations in the process of emodin biosynthesis.