Title :
Notice of Retraction
Accurate Localization and Function Analysis of the Potentially Mobile Genomic Islands in Pseudomonas aeruginosa PA7
Author :
Lei Song ; Huanyu Jia ; Xuehong Zhang
Author_Institution :
Sch. of Life Sci. & Biotechnol., Shanghai Jiaotong Univ., Shanghai, China
Abstract :
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
The mobile genomic island (GI) can keep dynamic balance between excision from and reintegration into the chromosome, and may be transferred into the new host. Twelve potentially mobile genomic islands, namely, PA7GI1-PA7GI12, which have clear flanking sequences, were detected in Pseudomonas aeruginosa PA7. HPr gene was first found as the integration site of a GI (PA7GI9). TCAACAA is presumed to be the cutting site of the integrase in PA7GI9. The cutting sites of the integrases in 4 GIs flanked by tRNA genes are the anti-codon loops of the tRNA sequences. PA7GI9 can be transferred between Betaproteobacteria and Gammaproteobacteria of Proteobacteria. Another novel genomic island (PA7GI3) also can be transferred among Proteobacteria, Actinobacteria, Verrucomicrobia and Acidobacteria. Through function analysis of PA7GI1, Pseudomonas aeruginosa PA7 was a super-high heavy metal ion (Hg2+) uptake strain and the sequence block of PA7GI1 was divided into five main regions: mobile element region, functional region, compensation region, protection region and repair region. It is demonstrated that the GI is the result of multiple rearranging gene to ensure normal metabolism of the strain and complete important biological function.
Keywords :
biology computing; genetics; genomics; microorganisms; molecular biophysics; Acidobacteria; Actinobacteria; Betaproteobacteria; Gammaproteobacteria; HPr gene; PA7GI1-PA7GI12; PA7GI9; Proteobacteria; Pseudomonas aeruginosa PA7; TCAACAA; Verrucomicrobia; anticodon loops; chromosome; integrase; mobile genomic island; tRNA genes; Bioinformatics; DNA; Genomics; Immune system; Mobile communication; Proteins;
Conference_Titel :
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-5088-6
DOI :
10.1109/icbbe.2011.5780034