Title :
Notice of Retraction
Preparation and Acute Toxicological Effect of Hydrolyzed Collagen from Tilapia Scales
Author_Institution :
Coll. of Food Sci. & Eng., Harbin Univ. of Commerce, Harbin, China
Abstract :
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Tilapia scales were chosen to prepare hydrolyzed collagen using Papain and Alcalase following by decalcification in HCl and demineralization in Ca (OH)2. The degree of hydrolysis was 23.58%. After dehydrated, the white powder of density, ash, moisture and protein content were 0.22g/mL, 4.7%, 1.4% and 96% respectively. As results of amino acid composition, the amount of Gly, Pro, Hpro and Glu is up to 58% Hydrolyzed collagen were given to ICR mouse at dose of 20 g/kg body weight in both male and female mice(n = 10 per sex). There were no difference in gross morphological, physiological, behavioral changes were closely observed for 14 days, and zero mortality was obtained.
Keywords :
aquaculture; biotechnology; calcium compounds; hydrogen compounds; microorganisms; toxicology; Alcalase; ICR mouse; Papain; amino acid composition; behavioral changes; decalcification; demineralization; gross morphological changes; hydrolysis; hydrolyzed collagen; physiological changes; tilapia scales; toxicological effect; Amino acids; Marine animals; Mice; Moisture; Production; Proteins; Skin;
Conference_Titel :
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-5088-6
DOI :
10.1109/icbbe.2011.5780072
