Notice of RetractionChromatin Organization in Different Types of Splicing Events

Notice of Retraction

After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.

We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.

Recent studies have demonstrated that pre-mRNA splicing is initiated during gene transcription. The cross-talk between chromatin organization and mRNA splicing has also been analyzed. But it is not clear whether chromatin organization is related with different types of splicing events. We previously investigated the length distribution of exons and flanking introns, nucleosome occupancy and histone modification in different types of splicing exons. Our data suggests that short exons with short flanking introns have a tendency to be more frequently retained as constitutive exons. Nucleosome positioning around exon is more likely to improve exons inclusion and splicing efficiency. Different histone modifications were also found in constitutive and alternative exons, suggesting a special role in alternative splicing.