DocumentCode :
3320291
Title :
Analytical Solution of Gene Regulatory Networks
Author :
Gelenbe, Erol
Author_Institution :
Imperial Coll. London, London
fYear :
2007
fDate :
23-26 July 2007
Firstpage :
1
Lastpage :
6
Abstract :
We study gene regulatory networks that include the effect of multiple binary interactions, when various genes can activate or inhibit other genes, as well as of ternary interactions where two genes jointly affect the level of activity of a third gene. We also prove that Boolean identities for the activation state of a gene in terms of the activation level of another set of genes, can be represented, so that the overall probability of activation of any gene in the network can be computed in the presence of logical dependencies, and excitatory-inhibitory interactions between genes.
Keywords :
genetic engineering; genetics; probability; Boolean identities; activation probability; excitatory-inhibitory interactions; gene regulatory networks; logical dependencies; multiple binary interactions; Biological information theory; Biological system modeling; Biology computing; Cells (biology); Computer networks; Continuous time systems; Negative feedback loops; Organisms; Proteins; Time factors;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Fuzzy Systems Conference, 2007. FUZZ-IEEE 2007. IEEE International
Conference_Location :
London
ISSN :
1098-7584
Print_ISBN :
1-4244-1209-9
Electronic_ISBN :
1098-7584
Type :
conf
DOI :
10.1109/FUZZY.2007.4295674
Filename :
4295674
Link To Document :
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