Title :
Notice of Retraction
Role of Listeria monocytogenes sigmaB in Antibiotic Resistance
Author :
Wang Li ; Feng Feifei ; Zhang Qiang ; Feng Xiaoqin ; Yin Xiaojiao ; Feng Yingying ; Zhou Qingchun ; Luo Qin
Author_Institution :
Hubei Key Lab. of Genetic Regul. & Integrative Biol., Central China Normal Univ., Wuhan, China
Abstract :
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Antibiotics resistance in the foodborne pathogen Listeria monocytogenes emerging in recent years increases a public health concern. In order to investigate the genetic mechanisms of antimicrobial response in L. monocytogenes, the ability of the stress responsive alternative Sigma factor mutant EGDeΔsigB tolerant to six different antibiotics was analyzed by minimal inhibitory concentration (MIC) and the growth assays. Our results showed that the MICs of EGDeΔsigB were significant lower than that of wild type EGDe in penicillin G, erythromycin, and gentamicin media. The growth of EGDeΔsigB was inhibited strongly in the four times MIC of the antibiotics tetracyclin HC1, Rifampicin and Ampicillin. All these data indicate that σB plays a very important role in L. monocytogenes antibiotics resistance.
Keywords :
antibacterial activity; cellular biophysics; drugs; genetics; microorganisms; molecular biophysics; Ampicillin; Listeria monocytogenes σB; Rifampicin; antibiotic resistance; antimicrobial response; erythromycin; foodborne pathogen; genetic mechanisms; gentamicin media; growth assays; minimal inhibitory concentration; penicillin G; stress responsive alternative Sigma factor mutant EGDeΔsigB; tetracyclin HC1; Antibiotics; Immune system; Microorganisms; Microwave integrated circuits; Pathogens; Strain; Stress;
Conference_Titel :
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-5088-6
DOI :
10.1109/icbbe.2011.5780233