Title :
Notice of Retraction
Characterization of Mx in White Leghorn and Expression in Escherichia coli
Author :
Yin, C.G. ; Cao, D.G. ; Zhao, G.P. ; Du, L.X.
Author_Institution :
Life Sci. & Eng. Dept., Jining Univ., Qufu, China
Abstract :
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Chicken Mx protein has been reported to confer positive antiviral activity to influenza virus and vesicular stomatitis virus in vitro. The full-length Mx cDNA (2729bp) was isolated from White Leghorn breed, then registered in the GenBank under the accession number EU348752.1. The ORF sequence (2118bp) of the Mx was successfully expressed in E.coli which was first reported. Western blotting analysis indicated that Mx protein of 75kDa can be specifically detected in E.coli. The gene structure, alignment of protein and cDNA sequence of different chickens and different species and the expression in the E.coli laid the foundation of extensive analysis of gene function and antiviral activity study of chicken.
Keywords :
DNA; biology computing; genetics; genomics; microorganisms; molecular biophysics; molecular configurations; proteins; GenBank; ORF sequence; Western blotting analysis; breed; cDNA sequence; chicken Mx protein; escherichia coli; gene structure; influenza virus; protein alignment; vesicular stomatitis virus; white leghorn; Amino acids; Bioinformatics; Genomics; Humans; Immune system; Influenza; Proteins;
Conference_Titel :
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-5088-6
DOI :
10.1109/icbbe.2011.5780260
