DocumentCode
3322411
Title
Notice of Retraction
Optimization of Enzymatic Conditions for Preparing Angiotensin I-Converting Enzyme Inhibitory Hydrolysates Derived from Oil-Tea (Camellia oleifera Abel) Seed Meal Protein
Author
Jijun Gong ; Zhonghai Li ; Haiyan Zhong ; Qizhi Long ; Guopu Ren
Author_Institution
Coll. of Food Sci. & Eng., Central South Univ. of Forestry & Technol., Changsha, China
fYear
2011
fDate
10-12 May 2011
Firstpage
1
Lastpage
5
Abstract
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
In this paper, the optimal protease and enzymatic conditions in the production of angiotensin I-converting enzyme (ACE) inhibitory hydrolysates derived from oil-tea seed meal (OTSM) protein was screened and optimized, respectively. The maximum ACE inhibition (ACEI) was obtained by alcalase hydrolysates in the screening experiment. Therefore, the alcalase was employed as enzyme in the optimization assay. With the aid of response surface methodology (RSM), the optimum hydrolysis conditions and statistical model for experimental validation were determined. The applicability of the model designed was confirmed and there was no significant difference (P>;0.05) between the final mean value of ACEI (79.25 % (n = 3)) and the predicted ACEI (77.78 %). According to the data shown in this work, it could be concluded that the alcalase hydrolysates derived from OTSM protein possessed highly suppressing activity against ACE in vitro and the model obtained through RSM was efficacious in predicting the ACEI in the preparation of ACE inhibitory hydrolysates.
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
In this paper, the optimal protease and enzymatic conditions in the production of angiotensin I-converting enzyme (ACE) inhibitory hydrolysates derived from oil-tea seed meal (OTSM) protein was screened and optimized, respectively. The maximum ACE inhibition (ACEI) was obtained by alcalase hydrolysates in the screening experiment. Therefore, the alcalase was employed as enzyme in the optimization assay. With the aid of response surface methodology (RSM), the optimum hydrolysis conditions and statistical model for experimental validation were determined. The applicability of the model designed was confirmed and there was no significant difference (P>;0.05) between the final mean value of ACEI (79.25 % (n = 3)) and the predicted ACEI (77.78 %). According to the data shown in this work, it could be concluded that the alcalase hydrolysates derived from OTSM protein possessed highly suppressing activity against ACE in vitro and the model obtained through RSM was efficacious in predicting the ACEI in the preparation of ACE inhibitory hydrolysates.
Keywords
biochemistry; enzymes; molecular biophysics; optimisation; ACE inhibition; Camellia oleifera Abet; OTSM protein; angiotensin I-converting enzyme; enzymatic conditions optimization; inhibitory hydrolysates; oil-tea seed meal protein; optimization assay; response surface methodology; Analysis of variance; In vitro; Peptides; Production; Proteins; Response surface methodology;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location
Wuhan
ISSN
2151-7614
Print_ISBN
978-1-4244-5088-6
Type
conf
DOI
10.1109/icbbe.2011.5780296
Filename
5780296
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