Title :
Numerical Simulations of the Non-Newtonian Blood Blow in Human Thoracic Aortic Dissection Based on CT Images
Author :
Yang, Hong ; Hong Yang
Author_Institution :
Dept. of Biophys., China Med. Univ., Shenyang, China
Abstract :
Combine medical images three-dimensional reconstruction technique and computational fluid dynamics (CFD) methods to perform simulation the Non-Newtonian blood fluid flow in descending thoracic aortic dissection, then analyzes the relation between the hemodynamic parameters of descending thoracic aortic dissection obtained by numerical simulation of blood flow based on CT images and the pathogenesis of aortic dissection disease. A Non-Newtonian blood model (the Generalised Power Law) is used to study the hemodynamic parameters during entire cardiac cycle. Calculated results for the Non-Newtonian blood flow show us the hemodynamic parameters in thoracic aortic is complex, such as the large changes in wall stress, multiple vortex phenomena at the openings, which support the view there is a certain relation between the complex blood flow of aortic dissection and the pathogenesis of aortic dissection disease.
Keywords :
blood vessels; computational fluid dynamics; computerised tomography; diseases; flow simulation; haemodynamics; medical computing; non-Newtonian flow; physiological models; vortices; 3D reconstruction technique; CFD; CT images; aortic dissection disease pathogenesis; arterial wall stress; computational fluid dynamics; descending thoracic aortic dissection; generalised power law model; hemodynamic parameters; human thoracic aortic dissection; nonNewtonian blood blow; numerical simulations; vortex phenomena; Biomedical imaging; Blood; Blood flow; Computational modeling; Numerical models; Solid modeling; Stress;
Conference_Titel :
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-5088-6
DOI :
10.1109/icbbe.2011.5780306