DocumentCode
3325059
Title
Notice of Retraction
The Inhibition of Tupistra chinensis Baker Extracts on Mice H22 Hepatocarcinoma Xenograft
Author
Wenfeng Huang
Author_Institution
Med. Coll., China Three Gorges Univ. (CTGU), Yichang, China
fYear
2011
fDate
10-12 May 2011
Firstpage
1
Lastpage
3
Abstract
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Tupistra chinensis Baker is a widely used medicinal plant in western area of China. In this study, we investigated the effect of Tupistra chinensis Baker extracts on mice H22 hepatocarcinoma xenograft. The mice H22 hepatocarcinoma xenograft animal model was made up firstly. And the mice were administrated by gavage with different concentrations of Tupistra chinensis Baker extracts for 15 days, and the xenograft growth condition, histological study and electron microscopy were used. Compared to model, Tupistra chinensis Baker extracts could significantly inhibit the xenograft growth. Big mass necroses were observed under the light microscope. Further electron microscope observation found that cancer cells apoptosis was severe. Our animal experiments demonstrated that Tupistra chinensis Baker extracts can inhibit the growth of H22 hepatocarcinoma xenograft probably through apoptosis.
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Tupistra chinensis Baker is a widely used medicinal plant in western area of China. In this study, we investigated the effect of Tupistra chinensis Baker extracts on mice H22 hepatocarcinoma xenograft. The mice H22 hepatocarcinoma xenograft animal model was made up firstly. And the mice were administrated by gavage with different concentrations of Tupistra chinensis Baker extracts for 15 days, and the xenograft growth condition, histological study and electron microscopy were used. Compared to model, Tupistra chinensis Baker extracts could significantly inhibit the xenograft growth. Big mass necroses were observed under the light microscope. Further electron microscope observation found that cancer cells apoptosis was severe. Our animal experiments demonstrated that Tupistra chinensis Baker extracts can inhibit the growth of H22 hepatocarcinoma xenograft probably through apoptosis.
Keywords
biochemistry; botany; cancer; cellular biophysics; pharmaceuticals; Tupistra chinensis Baker; Tupistra chinensis extracts; cancer cell apoptosis; electron microscopy; hepatocarcinoma animal model; hepatocarcinoma xenograft growth condition; hepatocarcinoma xenograft growth inhibition; hepatocarcinoma xenograft histology; medicinal plant; mice H22 hepatocarcinoma xenograft; Cancer; Electron microscopy; In vitro; Mice; Tumors;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location
Wuhan
ISSN
2151-7614
Print_ISBN
978-1-4244-5088-6
Type
conf
DOI
10.1109/icbbe.2011.5780439
Filename
5780439
Link To Document