Simulation of dynamic PET data from real MR acquisitions

Author

Tsoumpas, Charalampos ; Buerger, Christian ; King, Andrew P. ; Keereman, Vincent ; Vandenberghe, Stefaan ; Schulz, Volkmar ; Schaeffter, Tobias ; Marsden, Paul K.

Author_Institution

Sch. of Med., King´´s Coll. London, London, UK

fYear

2009

fDate

Oct. 24 2009-Nov. 1 2009

Firstpage

3065

Lastpage

3068

Abstract

We have implemented a scheme for simulating realistic dynamic PET data from real MR acquisitions. This toolkit uses a series of MR acquisitions, image registrations and segmentations. PET images are simulated assigning typical values to the segmented images, and manually inserting additional lesions. The data are simulated using analytic forward-projections (including attenuation) with STIR, providing a fast and simple simulation toolkit that can be used to efficiently study the performance of different reconstruction and motion and attenuation correction approaches for dynamic PET data.

Keywords

biomedical MRI; data acquisition; image motion analysis; image reconstruction; image registration; image segmentation; medical image processing; positron emission tomography; tumours; analytic forward-projections; attenuation correction; dynamic PET data; image motion; image reconstruction; image registrations; image segmentations; lesions; real MR acquisitions; Analytical models; Attenuation; Image motion analysis; Image reconstruction; Image registration; Image segmentation; Lesions; Motion analysis; Performance analysis; Positron emission tomography; MLEM; Motion Correction; PET; PET-MR; Reconstruction; STIR;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record (NSS/MIC), 2009 IEEE

Conference_Location

Orlando, FL

ISSN

1095-7863

Print_ISBN

978-1-4244-3961-4

Electronic_ISBN

1095-7863

Type

conf

DOI

10.1109/NSSMIC.2009.5401662

Filename

5401662