• DocumentCode
    3329458
  • Title

    Measurements of [11C]CO2 in exhaled air with a positron-sensitive single-wire proportional counter after i.v. injection of [11C]acetate

  • Author

    Sipila, Hannu T. ; Heselius, Sven-Johan ; Kalliokoski, Matti K. ; Kemppainen, Jukka ; Minn, Heikki ; Tolvanen, Tuula ; Roivainen, Anne

  • Author_Institution
    Turku PET Centre, Turku Univ. Hosp., Turku, Finland
  • fYear
    2011
  • fDate
    23-29 Oct. 2011
  • Firstpage
    2397
  • Lastpage
    2399
  • Abstract
    A positron-sensitive, large-window single-wire proportional counter was used for measurements of [11C]CO2 in exhaled air after i.v. injection of [11C]acetate. The performance of the proportional counter was studied using Geant4 and Garfield simulation tools as well as experimentally by injections of known amounts of radioactive gas into the measuring volume. The proportional counter was found to be sensitive enough for measuring the low concentrations of [11C]CO2 in the air exhaled by patients after i.v. injection of an 11C-labelled radiopharmaceutical. The limit of detection was 200 Bq/L for [11C]CO2.
  • Keywords
    biochemistry; biomedical measurement; chemical variables measurement; organic compounds; pneumodynamics; positron emission tomography; proportional counters; CO2; Garfield simulation; Geant4 simulation; acetate; carbon dioxide measurement; exhaled air; positron sensitive single wire proportional counter; radioactive gas; radiopharmaceutical; Heating;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE
  • Conference_Location
    Valencia
  • ISSN
    1082-3654
  • Print_ISBN
    978-1-4673-0118-3
  • Type

    conf

  • DOI
    10.1109/NSSMIC.2011.6152653
  • Filename
    6152653
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3329458