DocumentCode :
3329613
Title :
Construction of a pre-clinical High Resolution Tomographic Scintillation camera system
Author :
Peterson, M. ; Ljunggren, K. ; Palmer, Joseph ; Strand, S.-E. ; Miller, B.
Author_Institution :
Dept. of Med. Radiat. Phys., Lund Univ., Lund, Sweden
fYear :
2009
fDate :
Oct. 24 2009-Nov. 1 2009
Firstpage :
3670
Lastpage :
3671
Abstract :
We are constructing a High Resolution Tomographic Scintillation Camera System for small animal imaging. The system consists of a CsI(Tl) scintillator coupled to a military surplus image intensifier with a CCD camera focused on the output window. The system operates in photons counting mode and the spatial resolution is improved by centroid calculations for every photon interaction. The system can be mounted on an optical rail together with a pinhole collimator and a rotating table. A hot rod phantom was filled with 201Tl or 99mTc solute and imaged. The phantom rod diameters range from 1.1 to 1.6 mm. 64 projections were acquired (300 s/projection) with 1 mm pinhole insert. Data was reconstructed using an OSEM algorithm. Image data was corrected for decay, position non-linearities in image intensifier and the angular dependence of the pinhole. The reconstructed resolution is 1.3 mm (by visual inspection) for both 99mTc and 201Tl. Higher spatial resolution is achievable with smaller pinhole diameters. Future work includes optimizing spatial resolution and sensitivity of a single system using analytical calculations, experiments and simulations. With the conclusions drawn from those calculations we plan to construct a multi-camera system.
Keywords :
CCD image sensors; image reconstruction; medical image processing; phantoms; single photon emission computed tomography; solid scintillation detectors; CCD camera; CsI(Tl) scintillator; OSEM algorithm; centroid calculations; high resolution tomographic scintillation camera system; hot rod phantom; image correction; image reconstruction; military surplus image intensifier; pinhole collimator; rotating table; small animal imaging; Animals; Cameras; High-resolution imaging; Image intensifiers; Image reconstruction; Image resolution; Imaging phantoms; Optical imaging; Spatial resolution; Tomography; molecular imaging; single photon imaging; small animal SPECT;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Nuclear Science Symposium Conference Record (NSS/MIC), 2009 IEEE
Conference_Location :
Orlando, FL
ISSN :
1095-7863
Print_ISBN :
978-1-4244-3961-4
Electronic_ISBN :
1095-7863
Type :
conf
DOI :
10.1109/NSSMIC.2009.5401853
Filename :
5401853
Link To Document :
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