CMOS sensors for microscopy, spectrophotometry and as a transducer in biosensors

This paper reports a novel use of CMOS sensor technology in the development of microscopes, spectrophotometers and biosensors. A webcam CMOS Sensor was exploited to gain sufficient magnifications of carbon fibers (diameter 7 micrometers) and permanent slides of rat brain sections excluding use of any lens system for the purpose. Magnifications around 150 to 200 times were achieved using given CMOS sensor. In addition, different concentrations of yeast cell solutions were observed in a spectrophotometric setup prepared. Intensity values were collected using the software analysis of data provided by CMOS chip respectively. Also liquid films of yeast cells prepared over glass surfaces were analyzed using this CMOS chip in a similar study. This was to demonstrate CMOS sensor´s potential applicability in development of biosensor devices. Finally as a conclusion these studies showed variety of potential applications of CMOS sensors such as study of small sized particles and materials, measuring concentrations of solutions and in development of cell detectors and monitoring devices.