Notice of RetractionProtective Effect of Essential Oil from Zingiber Officinale (Zingiberaceae) on Acute Alcohol-Induced Liver Injury in Mice

Notice of Retraction

After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.

We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

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Oxidative stress and lipid abnormalities after ethanol consumption are suggested to play a key role in the development of alcoholic liver injury. We investigated the induction of oxidative damage in association with triglyceride abnormalities in hepatic concentrations mice challenged with ethanol administration. Also the protective effect of ginger essential oil (GEO) extracted with supercritical carbon dioxide against ethanol-induced liver injury was determined. Hepatic malondialdehyde, triglyceride level and the fat vacuoles score were increased significantly by ethanol administration. Ethanol administration decreased hepatic glutathione reduced level. GEO supplied through gavage for 30 days attenuated the induction of alcoholic liver injury. This study demonstrated that GEO extract with supercritical carbon dioxide caused a decrease in lipid peroxidation, an increase of plasma antioxidant capacity and a reduction in hepatic injury.