Title :
Fully integrated micro biochemical laboratory using Biochemical IC chips
Author :
Ikuta, Koji ; Takahashi, Atsushi ; Ikeda, Kota ; Maruo, Shoji
Author_Institution :
Dept. of Micro Syst. Eng., Nagoya Univ., Japan
Abstract :
We have developed a fully integrated protein synthesis system including micropumps by using "Biochemical IC chips" proposed by Ikuta. The builtin micropumps driven by shape memory alloy (SMA) microactuators provide sufficiently long lifetime and flow rate to synthesize protein. The luminous protein "Luciferase" of firefly was successfully synthesized from DNA in seven hours with the built-in micropumps. The palm-top protein synthesis devices are promising and powerful tools for not only order-made examination but also implantable/wearable medical devices in the near future.
Keywords :
DNA; biosensors; chemical analysis; microfluidics; micropumps; proteins; Biochemical IC chips; flow rate; fully integrated micro biochemical laboratory; implantable/wearable medical devices; long lifetime; luminous protein Luciferase; micropumps; palm-top protein synthesis devices; protein synthesis system; shape memory alloy microactuators; Application specific integrated circuits; Inductors; Integrated circuit synthesis; Laboratories; Micropumps; Protein engineering; Pumps; Reservoirs; Shape memory alloys; Valves;
Conference_Titel :
Micro Electro Mechanical Systems, 2003. MEMS-03 Kyoto. IEEE The Sixteenth Annual International Conference on
Print_ISBN :
0-7803-7744-3
DOI :
10.1109/MEMSYS.2003.1189783