Automated DNA sequencing on gel images by digital techniques

Author

Zhu, S.F. ; Zhang, Y.T.

Author_Institution

Dept. of Biomed. Eng., Zhejiang Med. Univ., Hangzhou, China

Volume

2

fYear

1998

fDate

29 Oct-1 Nov 1998

Firstpage

1076

Abstract

DNA sequencing is one of the important aspects of genetic engineering. We applied digital image processing techniques to this study, and also introduced a recurring algorithm of adaptive segmentation to perform such sequencing. As shown in the experimental results, this method has its own characteristic. Specifically, it enhances the recognition of DNA sequence to become quicker and more efficient. Since the future of biotechnology is very promising, we believe that further research in this field using digital method is worthwhile

Keywords

DNA; biochemistry; biological techniques; biology computing; biotechnology; electrophoresis; genetics; image segmentation; medical image processing; molecular configurations; Gaussian filtering; adaptive segmentation; automated DNA sequencing; digital image processing; gel images; genetic engineering; recurring algorithm; sequence recognition; single fragment reading; Amino acids; Biological information theory; Biomedical engineering; Biomedical optical imaging; DNA; Digital images; Genetic engineering; Optical distortion; Optical filters; Sequences;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE

Conference_Location

Hong Kong

ISSN

1094-687X

Print_ISBN

0-7803-5164-9

Type

conf

DOI

10.1109/IEMBS.1998.745639

Filename

745639