Clinical inquiry & computer simulation of RR-QT system suggest functional long QT episodes in borderline subjects

Author

Dinca-Panaitescu, S. ; Ionescu, D.-D. ; Achim, A. ; Dinca-Panaitescu, M. ; Negoescu, R.

Author_Institution

Dept. of Cardiovascular Prophylaxy, Aisteda Univ., Romania

fYear

1998

fDate

29 Oct-1 Nov 1998

Firstpage

243

Abstract

We report direct experimental estimations of time constant in RR-QT system (τ_QT) using pharmacological or electrophysiological manipulations of heart rate (HR). We find by means of using computer simulation that τ_QT size may be introduced in borderline subjects (QTc>450 ms for males) under current life stress episodes of functional long QT with “risk surface” comparable with that of patently long QT patients

Keywords

electrocardiography; medical signal processing; time series; RR-QT system; borderline subjects; clinical inquiry; computer simulation; electrophysiological manipulation; functional long QT episodes; heart rate; life stress episodes; pharmacological manipulation; right atrial pacing; risk surface; thoracic ECG; time constant estimation; time series; vagal blockade; Biomedical informatics; Cardiology; Cardiovascular diseases; Computer simulation; Diabetes; Heart rate; Life estimation; Public healthcare; Silicon compounds; Stress;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE

Conference_Location

Hong Kong

ISSN

1094-687X

Print_ISBN

0-7803-5164-9

Type

conf

DOI

10.1109/IEMBS.1998.745885

Filename

745885