Title :
A cardiovascular control model of 1/f fluctuations in heart rate variability
Author :
Nakao, Mitsuyuki ; Takizawa, Tomokazu ; Nakamura, Kazuhiro ; Katayama, Norihiro ; Yamamoto, Mitsuaki
Author_Institution :
Graduate Sch. of Inf. Sci., Tohoku Univ., Sendai, Japan
fDate :
29 Oct-1 Nov 1998
Abstract :
Recently, the 1/f fluctuations in heart rate variabilities (HRV) of human and animals have been empirically established. They reflect various regulatory mechanisms such as the autonomic nervous system, hormonal systems, and variations in physiological states. So far, researches studying the dynamics of HRV have not directly reached the control rationale of the cardiovascular system, which have been done rather for assessing the above regulatory functions. Here, in order to study control rationale of the cardiovascular system, relationship between the control criteria and the resulting dynamics is investigated by applying an optimal control on a newly developed cardiovascular model. The simulation results suggest that the 1/f fluctuations in HRV is generated under loose control criteria against deviations of blood pressure from its working point in contrast with rigid controls performed in artificial systems
Keywords :
biocontrol; cardiovascular system; haemodynamics; optimal control; physiological models; 1/f fluctuations; artificial systems; autonomic nervous system; blood pressure deviations; cardiovascular control model; cardiovascular model; control criteria; heart rate variability; hormonal systems; regulatory functions; simulation results; Animals; Autonomic nervous system; Cardiology; Cardiovascular system; Fluctuations; Heart rate; Heart rate variability; Humans; Optimal control; Pressure control;
Conference_Titel :
Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE
Conference_Location :
Hong Kong
Print_ISBN :
0-7803-5164-9
DOI :
10.1109/IEMBS.1998.745896
