An improved algorithm for the design of individually optimized dialysis profiles

Author

Bachhiesl, P. ; Scharfetter, H. ; Kappel, F. ; Hutten, H.

Author_Institution

Dept. of Biomed. Eng., Graz Univ. of Technol., Austria

Volume

5

fYear

1996

fDate

31 Oct-3 Nov 1996

Firstpage

1806

Abstract

An efficient algorithm for the optimization of process parameters during dialysis has been developed. It is possible to compute optimal concentrations of electrolytes in dialysis by solving a tracking problem for distinguished dynamic variables, which are indirectly influencing the status of the patient and can directly be modelled. The tracking problem was treated as a dynamic optimization problem, which has been solved by the application of a modified continuous descent procedure, which is known from the theory of unconstrained static minimization. The used method is characterized by its simple mode of application, short solution time and moderate storage need. Especially in cases of contradictional requirements for the desired time courses of a dialysis session the used method performs well

Keywords

blood; electrolytes; optimisation; patient treatment; blood filtration; dialysis session desired time courses; efficient algorithm; individually optimized dialysis profiles design; modified continuous descent procedure; optimal electrolyte concentrations computation; patient status; unconstrained static minimization theory; Algorithm design and analysis; Biomedical computing; Biomedical engineering; Blood; Design optimization; Mathematics; Medical treatment; Open loop systems; Optimal control; Trajectory;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE

Conference_Location

Amsterdam

Print_ISBN

0-7803-3811-1

Type

conf

DOI

10.1109/IEMBS.1996.646265

Filename

646265