DocumentCode
3342833
Title
Notice of Retraction
Human Osteosarcoma Cell Functions Enhanced by Nanoscale TiO2 with Different Surface Topography
Author
Xiaoling Xiang ; Mingdi Jiang ; Bing Han ; Liting Yao ; Zhihong Zhu ; Xu Yang
Author_Institution
Hubei Key Lab. of Genetic Regul. & Integrative Biol., Huazhong Normal Univ., Wuhan, China
fYear
2011
fDate
10-12 May 2011
Firstpage
1
Lastpage
4
Abstract
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Three types of titanium (Ti) based nanoscale titania (TiO2) were produced by controlling the reaction conditions, including TiO2 nanotubes, TiO2 nanonetworks and TiO2 nanoparticles. Human Osteosarcoma cells (MG63) were used in this study to evaluate the bioactivity and cytocompatibility of the new materials. Compared to flat Ti, cell adhesion of the materials coated with nanoscale TiO2 was significantly enhanced after 2h, 24h, and 72 h of co-incubation, according to SEM photographs. More importantly, compare to the control group, the lactate dehydrogenase (LDH) released into the culture media and the absorbance of MTT showed no obvious difference after 72 h of co-incubation. Therefore, it is suggested that nanoscale TiO2 is a bioactive and cytocompatible biomedical material.
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Three types of titanium (Ti) based nanoscale titania (TiO2) were produced by controlling the reaction conditions, including TiO2 nanotubes, TiO2 nanonetworks and TiO2 nanoparticles. Human Osteosarcoma cells (MG63) were used in this study to evaluate the bioactivity and cytocompatibility of the new materials. Compared to flat Ti, cell adhesion of the materials coated with nanoscale TiO2 was significantly enhanced after 2h, 24h, and 72 h of co-incubation, according to SEM photographs. More importantly, compare to the control group, the lactate dehydrogenase (LDH) released into the culture media and the absorbance of MTT showed no obvious difference after 72 h of co-incubation. Therefore, it is suggested that nanoscale TiO2 is a bioactive and cytocompatible biomedical material.
Keywords
adhesion; biochemistry; biological specimen preparation; biomechanics; biomedical materials; bone; cancer; cellular biophysics; nanomedicine; nanoparticles; nanotubes; sorption; titanium compounds; MG63 cells; MTT absorbance; SEM; TiO2; bioactivity; cell adhesion; culture media; cytocompatible biomedical material; human osteosarcoma cell functions; lactate dehydrogenase; nanoparticles; nanotubes; reaction conditions; surface topography; time 2 h to 72 h; titanium based nanoscale titania; Adhesives; Bones; Materials; Nanoparticles; Nanoscale devices; Nanotubes; Surface topography;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location
Wuhan
ISSN
2151-7614
Print_ISBN
978-1-4244-5088-6
Type
conf
DOI
10.1109/icbbe.2011.5781373
Filename
5781373
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