Notice of RetractionResponse of Cytochrome P450 in Earthworms Exposed to Arsanilic Acid Contaminated Soils

Notice of Retraction

After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.

We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

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Arsanilic acid is a normal used feed additive in animal breeding. Almost no studies have concerned its effect on the enzymatic activities in earthworms. In present study, we investigated the activities of three important enzymes in cytochrome P450 system: benzoxy- resorufin-O -dealkylase (BROD), Pentoxyresorufin -O- dealkylase (PROD), Methoxyresorufin-O -deethylase (MROD) in earthworm Eisenia andrei exposed to arsanilic acid. 5 different concentration groups of arsanilic acid were designed to simulate the process that arsanilic acid was discharged into soil with animal manure. BROD, PROD, MROD activities in worms were respectively measured in different time after exposure. The results showed that all the three enzymes in worms were inhibited by arsanilic acid. The inhibition extents were BROD>;PROD>; MROD. It also showed time or dose dependent is some treatments. As a conclusion, the three enzymes might be used as biomarker of arsanilic acid contamination in soils.