DocumentCode
3343045
Title
Notice of Retraction
Response of Cytochrome P450 in Earthworms Exposed to Arsanilic Acid Contaminated Soils
Author
Yinsheng Li ; Hao Tang ; Xiuhong Wang ; Weiguo Qiu ; Jiangping Qiu
Author_Institution
Sch. of Agric. & Biol., Shanghai Jiao Tong Univ., Shanghai, China
fYear
2011
fDate
10-12 May 2011
Firstpage
1
Lastpage
4
Abstract
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Arsanilic acid is a normal used feed additive in animal breeding. Almost no studies have concerned its effect on the enzymatic activities in earthworms. In present study, we investigated the activities of three important enzymes in cytochrome P450 system: benzoxy- resorufin-O -dealkylase (BROD), Pentoxyresorufin -O- dealkylase (PROD), Methoxyresorufin-O -deethylase (MROD) in earthworm Eisenia andrei exposed to arsanilic acid. 5 different concentration groups of arsanilic acid were designed to simulate the process that arsanilic acid was discharged into soil with animal manure. BROD, PROD, MROD activities in worms were respectively measured in different time after exposure. The results showed that all the three enzymes in worms were inhibited by arsanilic acid. The inhibition extents were BROD>;PROD>; MROD. It also showed time or dose dependent is some treatments. As a conclusion, the three enzymes might be used as biomarker of arsanilic acid contamination in soils.
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Arsanilic acid is a normal used feed additive in animal breeding. Almost no studies have concerned its effect on the enzymatic activities in earthworms. In present study, we investigated the activities of three important enzymes in cytochrome P450 system: benzoxy- resorufin-O -dealkylase (BROD), Pentoxyresorufin -O- dealkylase (PROD), Methoxyresorufin-O -deethylase (MROD) in earthworm Eisenia andrei exposed to arsanilic acid. 5 different concentration groups of arsanilic acid were designed to simulate the process that arsanilic acid was discharged into soil with animal manure. BROD, PROD, MROD activities in worms were respectively measured in different time after exposure. The results showed that all the three enzymes in worms were inhibited by arsanilic acid. The inhibition extents were BROD>;PROD>; MROD. It also showed time or dose dependent is some treatments. As a conclusion, the three enzymes might be used as biomarker of arsanilic acid contamination in soils.
Keywords
soil; soil pollution; animal breeding; animal manure; arsanilic acid contaminated soil; arsanilic acid contamination; biomarker; cytochrome P450 system; earthworms; enzymatic activity; feed additive; Animals; Biochemistry; Chemicals; Contamination; Feeds; Grippers; Soil;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location
Wuhan
ISSN
2151-7614
Print_ISBN
978-1-4244-5088-6
Type
conf
DOI
10.1109/icbbe.2011.5781383
Filename
5781383
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