DocumentCode
3343881
Title
Notice of Retraction
Reproductive Toxicity of Anatase TiO2 Nanoparticles in Caenorhabditis elegans
Author
Zhang, W.W. ; Tong, L.P. ; Guo, X.Y. ; Wang, Lingfeng ; Wu, R.Q. ; Zhao, G.P. ; Wang, X.F. ; Du, Honglei ; Wu, L.J. ; Xu, Aixia
Author_Institution
Key Lab. of Ion Beam Bioeng., CAS, Hefei, China
fYear
2011
fDate
10-12 May 2011
Firstpage
1
Lastpage
4
Abstract
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
The potential harmful effects of manufactured nanoparticles have caused great attention in recent years. However, the particle size effect on the toxicity of nanoparticles is still largely unknown. In the present study, we investigated the physicochemical properties of anatase titanium dioxide nanoparticles (TiO2) at either 5 nm or 40 nm and their reproductive toxicity effects on Caenorhabditis elegans. There was a dose-dependent increase of germ cell death in C. elegans exposed to 5 nm TiO2 at graded concentrations ranging from 0.1 to 10 μg/mL for 24 h. The brood size was dramatically decreased in a dose-dependent manner in C. elegans exposed to TiO2 at 5 nm, while the brood size was not much altered by TiO2 at 40 nm. Our data clearly demonstrated that the particle size played an essential role in the reproductive toxicity of TiO2 nanoparticles in C. elegans.
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
The potential harmful effects of manufactured nanoparticles have caused great attention in recent years. However, the particle size effect on the toxicity of nanoparticles is still largely unknown. In the present study, we investigated the physicochemical properties of anatase titanium dioxide nanoparticles (TiO2) at either 5 nm or 40 nm and their reproductive toxicity effects on Caenorhabditis elegans. There was a dose-dependent increase of germ cell death in C. elegans exposed to 5 nm TiO2 at graded concentrations ranging from 0.1 to 10 μg/mL for 24 h. The brood size was dramatically decreased in a dose-dependent manner in C. elegans exposed to TiO2 at 5 nm, while the brood size was not much altered by TiO2 at 40 nm. Our data clearly demonstrated that the particle size played an essential role in the reproductive toxicity of TiO2 nanoparticles in C. elegans.
Keywords
biotechnology; health hazards; microorganisms; nanoparticles; titanium compounds; toxicology; Caenorhabditis elegans; TiO2; anatase titanium dioxide nanoparticles; germ cell death; harmful effects; physicochemical properties; reproductive toxicity; Cadaver; Humans; Nanomaterials; Nanoparticles; Stress; Titanium; Toxicology;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location
Wuhan
ISSN
2151-7614
Print_ISBN
978-1-4244-5088-6
Type
conf
DOI
10.1109/icbbe.2011.5781429
Filename
5781429
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