Title :
A resting-state fMRI study of patients with HIV infection based on regional homogeneity method
Author :
Wenjuan Qiu ; Bin Yan ; Jianxin Li ; Li Tong ; Ling Wang ; Dapeng Shi
Author_Institution :
Nat. Digital Switching Syst. Eng. & Technol. Res. Center, Zhengzhou, China
Abstract :
In this study, the Regional Homogeneity (ReHo) approach was used to investigate the abnormal brain areas in individuals infected with Human Immunodeficiency Virus (HIV) compared with the controls, on the resting state with fMRI. Significantly decreased brain regions were found at multiple brain locations. However, no increased brain region appeared. These detected differences provided additional imaging evidence that HIV virus could cause serious damage to the human nervous system and cognitive abnormalities commonly occur in patients with HIV infection.
Keywords :
biomedical MRI; brain; cognition; diseases; medical image processing; neurophysiology; patient diagnosis; HIV infection; abnormal brain areas; brain locations; cognitive abnormalities; human immunodeficiency virus; human nervous system; regional homogeneity method; resting-state fMRI; Acquired immune deficiency syndrome; Brain; Dementia; Human immunodeficiency virus; Magnetic resonance imaging; HIV; Regional Homogeneity; Resting-state; fMRI;
Conference_Titel :
Natural Computation (ICNC), 2011 Seventh International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-9950-2
DOI :
10.1109/ICNC.2011.6022180
