Title :
Increase in mutations by exposure of mammalian cells to ELF magnetic fields
Author :
Miyakoshi, Junji ; Kitagawa, Kaori ; Yamagishi, Nobuyuki ; Shibata, Toru ; Takebe, Hiraku
Author_Institution :
Dept. of Radiation Genetics, Kyoto Univ., Japan
fDate :
31 Oct-3 Nov 1996
Abstract :
Exposure to extremely low frequency magnetic fields (ELFMF) of 50 Hz and 400 mT induced mutations in the hypoxanthine-guanine phosphoribosyl transferase gene of human melanoma MeWo cells. The mutation frequency was enhanced both by increasing the exposure period and the induced current intensity. DNA replication error is suspected to cause the mutations produced by ELFMF exposure
Keywords :
DNA; biological effects of fields; biomagnetism; cellular effects of radiation; genetics; magnetic field effects; 400 mT; 50 Hz; DNA replication error; ELF magnetic fields exposure effects; cellular radiation biology; human melanoma MeWo cells; hypoxanthine-guanine phosphoribosyl transferase gene; induced current intensity; mammalian cells; mutation frequency; mutations increase; Cancer; Cells (biology); DNA; Frequency; Genetic mutations; Geophysical measurement techniques; Ground penetrating radar; Humans; Magnetic fields; Malignant tumors;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.646292
