Notice of RetractionConstruction of Recombinant Rabbit Hemorrhagic Disease Virus (RHDV) Vaccine Using Myxoma Virus (MV) as a Vector

Notice of Retraction

After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.

We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.

Rabbit hemorrhagic disease virus (RHDV) and myxoma virus (MV) are the two main viruses that cause serious virus diseases in rabbit population. MV, a pox virus, has been proved to be a good recombinant vaccine vector. In this study we have developed a recombinant virus using MV as a vector against both the myxomatosis and rabbit hemorrhagic disease (RHD). We used the nonessential gene MST3N of MV as the insertion site. The recombinant viruses expressed the RHDV major capsid protein (VP60) and the selectable marker GFP. The pure recombinant viruses were achieved after several rounds of plaque screening. Replication of MST3N-knockout recombinant virus MV-VP60 in Rabbit kidney cell (RK13) was unimpaired, compared with wild type virus MV.