Title :
Application of an adaptive digital filter to resistive pulse detection: application to passage of erythrocytes through an oligopore filter
Author :
Kehli, A. ; Senaoui, M. ; Larouk, A. ; Pautou, C. ; Boynard, M.
Author_Institution :
Lab. de Biophys. Appl., Univ. Rene Descartes, Paris, France
fDate :
31 Oct-3 Nov 1996
Abstract :
In the present paper, the authors propose as an alternative to analog circuits, a numerical method based on an adaptive digital filter to detect each resistive pulse caused by the passage of individual red blood cells (RBC) through an oligopore filter. The cell transit analyser (CTA) was used. Application of the method shows that: 1. Baseline time variations of the signal are removed and 2. The signal to noise ratio (SNR) is increased. The method is well adapted to extract other pulse features to characterize red cells in term of their deformability
Keywords :
adaptive filters; biological techniques; cellular transport; digital filters; haemorheology; adaptive digital filter; baseline time variations; cell deformability; cell transit analyser; erythrocytes passage; oligopore filter; pulse features extraction; red cells characterization; resistive pulse detection; signal to noise ratio; Adaptive filters; Biomembranes; Digital filters; Erbium; Frequency; Pulse circuits; Pulse measurements; Pulse shaping methods; Red blood cells; Signal to noise ratio;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.646311
