Laser-induced in vivo oxyhemoglobin photodissociation and its application for local tissue oxygenation

Author

Asimov, M.M.

Author_Institution

B.I. Stepanov Inst. of Phys., Nat. Acad. of Sci. of Belarus, Minsk

fYear

2008

fDate

Sept. 29 2008-Oct. 4 2008

Firstpage

68

Lastpage

70

Abstract

A novel method of local tissue oxygenation based on laser-induced in vivo photodissociation of oxyhemoglobin in cutaneous blood vessels is proposed. Dependents the value of additional oxygen extraction from oxyhemoglobin on the laser wavelength, irradiation time and the oxygen diffusion in different tissues are shown. The results of experimental study and computer modeling the kinetics of tissue oxygen distribution from blood plasma are presented. New laser-optical technology of local tissue oxygenation and elimination of hypoxia at irradiation zone is proposed. Different aspects of biomedical applications of the proposed new technology for elimination of local tissue hypoxia are discussed.

Keywords

bio-optics; biological tissues; blood vessels; photodissociation; biomedical applications; blood plasma; blood vessels; hypoxia elimination; laser-optical technology; local tissue oxygenation; oxygen extraction; oxyhemoglobin photodissociation; tissue oxygen distribution; Application software; Biomedical computing; Blood vessels; Distributed computing; In vivo; Kinetic theory; Laser beam cutting; Laser modes; Plasma applications; Plasma waves; hypoxia; laser therapy; oxyhemoglobin; photodissociation; tissue oxygenation;

fLanguage

English

Publisher

ieee

Conference_Titel

Advanced Optoelectronics and Lasers, 2008. CAOL 2008. 4th International Conference on

Conference_Location

Crimea

Print_ISBN

978-1-4244-1973-9

Electronic_ISBN

978-1-4244-1974-6

Type

conf

DOI

10.1109/CAOL.2008.4671859

Filename

4671859