Title :
Biological characterizations of hyaluronic acid hydrogel particles
Author :
Shin, Chulho ; Kim, Sumi ; Jo, Seongyeon ; Noh, Insup
Author_Institution :
Department of chemical Engineering, Seoul National University of Science & Technology, 138 Gongnung-gil, Nowon-gu, 139-743 Republic of Korea
Abstract :
Hyaluronic acid (HA), an anionic polysaccharide, is widely distributed in extracellular matrix of connective tissues. Applications of HA as a drug carrier have been recognized as an important polymer in cell therapy and tissue engineering. Fabrications of nano- or micro- hyaluronic acid particle were performed for its possible application as a drug carrier. HA particles were fabricated by employing untrasonic method. The HA hydrogel particles were evaluated by measuring their swelling and release of model drugs. Its morphological properties were also evaluated by observing with LM and SEM. Biological properties of the HA particles were performed with assays of MTT, BrdU, Neutral red.
Keywords :
Atmospheric measurements; Biological system modeling; Biomedical measurement; Nanobioscience; Particle measurements; Ultrasonic variables measurement;
Conference_Titel :
Nanotechnology Materials and Devices Conference (NMDC), 2011 IEEE
Conference_Location :
Jeju
Print_ISBN :
978-1-4577-2139-7
DOI :
10.1109/NMDC.2011.6155292
