Title :
Porous PLGA microspheres with BMP-2 releasing polyphosphate-functionalized nano-hydroxyapatite for enhanced bone regeneration
Author :
Koo, Ahn Na ; Lee, Sang Cheon
Author_Institution :
Department of Maxillofacial Biomedical Engineering, Kyung Hee University, Seoul 130-701, Korea
Abstract :
We report on bone-regenerative porous microspheres surface-decorated with polyphosphate-functionalized nano-hydroxyapatite (n-HAp) that can controllably release bone morphogenetic protein-2 (BMP-2). n-HAp was immobilized onto the pore surface of microspheres and could control the loading and the release of BMP-2.
Keywords :
Adsorption; Biomedical imaging; Polymers;
Conference_Titel :
Nanotechnology Materials and Devices Conference (NMDC), 2011 IEEE
Conference_Location :
Jeju
Print_ISBN :
978-1-4577-2139-7
DOI :
10.1109/NMDC.2011.6155386
