Bioprocess automation using new online sensors

Author

Jiang, Junfeng ; Fan, Shunjie ; Kong, Bing ; Cai, Haoyuan ; Guo, Min ; Zhuo, Vue

Author_Institution

Corp. Technol., Siemens Ltd., China, Beijing, China

fYear

2009

fDate

9-12 Aug. 2009

Firstpage

910

Lastpage

914

Abstract

An automation system for bioprocess monitoring and control, based on the distributed control system SIMATIC PCS7 and new online sensors, is introduced. The system realizes on-line monitoring of O₂ and CO₂ concentrations in the exhaust gas, cell density and size during fermentation processes by new instruments. Different fermentation phases can be clearly identified using the newly developed online sensor, which is ideal for the implementation of advanced process control strategies. Instrumentation, automation, and experimental results are presented to show the effectiveness of the control system.

Keywords

biotechnology; chemical sensors; computerised monitoring; distributed control; fermentation; process control; process monitoring; CO₂; O₂; SIMATIC PCS7; bioprocess automation system; bioprocess control; bioprocess monitoring; cell density; distributed control system; exhaust gas; fermentation processes; online monitoring; online sensors; Automatic control; Automation; Biosensors; Control systems; Distributed control; Instruments; Monitoring; Programmable control; Sensor systems; Temperature control; Bioprocess; Distributed Control System (DCS); fermentation; online sensor;

fLanguage

English

Publisher

ieee

Conference_Titel

Mechatronics and Automation, 2009. ICMA 2009. International Conference on

Conference_Location

Changchun

Print_ISBN

978-1-4244-2692-8

Electronic_ISBN

978-1-4244-2693-5

Type

conf

DOI

10.1109/ICMA.2009.5246326

Filename

5246326