Experimental validation of a nonlinear coded excitation method for contrast imaging

Author

Borsboom, Jerome ; Chin, Chien Ting ; De Jong, Nico

Author_Institution

Dept. of Cardiology & Exp. Echocardiography, Erasmus MC, Rotterdam, Netherlands

Volume

2

fYear

2002

fDate

8-11 Oct. 2002

Firstpage

1933

Abstract

The amount of harmonics generated by a contrast agent bubble is mainly dependent on peak bubble wall excursion. As we have previously shown for a single bubble, using chirps as the excitation signal improves both the linear and the non-linear response. Computer simulations of contrast bubble clouds show an increase of 10-13 dB in response, comparing pulsed excitations with chirped excitations that have equal bandwidths and peak amplitudes. Experimental results from water tank measurements with SonoVue™ contrast agent are in agreement with computer simulations showing better signal to noise ratio and an increase of ∼12 dB in second harmonic between pulse and chirp.

Keywords

biomedical measurement; biomedical ultrasonics; chirp modulation; ultrasonic measurement; SonoVue™ contrast agent; chirps; contrast imaging; equal bandwidths; nonlinear coded excitation method; peak amplitudes; peak bubble wall excursion; second harmonic; signal to noise ratio; Bandwidth; Chirp; Computational modeling; Computer simulation; Frequency; Pulse measurements; Scattering; Signal resolution; Signal to noise ratio; Ultrasonic imaging;

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics Symposium, 2002. Proceedings. 2002 IEEE

ISSN

1051-0117

Print_ISBN

0-7803-7582-3

Type

conf

DOI

10.1109/ULTSYM.2002.1192677

Filename

1192677