Title :
Scanning Magnetic Tunnel Junction Sensor for the Detection of Magnetically Labeled DNA Microarray
Author :
Chan, Mei-Lin ; Jaramillo, Gerardo M. ; Horsley, David A.
Author_Institution :
Univ. of California Davis, Davis
Abstract :
In this paper, we introduce a magnetic scanning probe microscope based on a single magnetic tunnel junction (MTJ) sensor with a sensitivity of 4 V / mT to detect magnetic particles on DNA microarray. We demonstrate the direct measurement of the magnetic dipole fields associated with both micron size ferromagnetic nickel thin film patterns and monodispersed paramagnetic particles tagged to surface immobilized DNA by large area 2D scanning of sensor over the sample with scan speed of ~500 mu m/s.
Keywords :
DNA; biosensors; ferromagnetic materials; magnetic sensors; magnetic tunnelling; ferromagnetic nickel thin film; magnetic dipole fields; magnetic scanning probe microscope; magnetically labeled DNA microarray; paramagnetic particles; scanning magnetic tunnel junction sensor; surface immobilized DNA; Area measurement; DNA; Magnetic field measurement; Magnetic force microscopy; Magnetic particles; Magnetic sensors; Magnetic tunneling; Probes; Thin film sensors; Velocity measurement; DNA microarray; Magnetic Particles; Magnetic Scanning Microscope; Magnetic Tunnel Junction (MTJ);
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International
Conference_Location :
Lyon
Print_ISBN :
1-4244-0842-3
Electronic_ISBN :
1-4244-0842-3
DOI :
10.1109/SENSOR.2007.4300080
