Title :
Kinetic modeling of rubidium during hemodialysis
Author :
Scharfetter, H. ; Krachler, M. ; Wirnsberger, G.H. ; Holzer, H. ; Hutten, H.
Author_Institution :
Inst. of Biomed. Eng., Tech. Univ. Graz, Austria
Abstract :
A multicompartment model for the exchange mechanisms of Rb+ during dialysis has been developed. The ion is assumed to follow the same kinetics as K+. Electrodiffusion and active transport across the cell membranes as well as convective processes due to differently perfused tissue groups have been considered. A first clinical evaluation revealed a good agreement between simulated and measured data
Keywords :
biodiffusion; bioelectric phenomena; biomembrane transport; blood; convection; patient treatment; physiological models; rubidium; K; K+; Rb; Rb+ exchange mechanisms; active transport; convective processes; differently perfused tissue groups; electrodiffusion; hemodialysis; kinetic modeling; measured data; multicompartment model; simulated data; Biochemical analysis; Biomedical engineering; Biomedical measurements; Biomembranes; Blood flow; Cells (biology); Chemistry; Extracellular; Kinetic theory; Permeability;
Conference_Titel :
Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
Print_ISBN :
0-7803-4262-3
DOI :
10.1109/IEMBS.1997.758775
