Title :
The work of breathing in a nonlinear model of respiratory mechanics
Author :
Athanasiades, A. ; Ghorbel, F. ; Clark, J.W., Jr. ; Niranjan, S.C. ; Liu, C.H. ; Zwischenberger, J.B. ; Bidani, A.
Author_Institution :
Dept. of Mech. Eng., Rice Univ., Houston, TX, USA
Abstract :
Analytical expressions are derived for the work of breathing (WOB) and are subsequently evaluated for a typical pulmonary function laboratory test that includes tidal breathing, panting and the forced vital capacity maneuvers. The analysis is based on a nonlinear model of respiratory mechanics that successfully mimics information presented in the conventional Campbell diagram, which is often used to graphically estimate WOB. In addition, the model reveals the partitioning of elastic WOB among the collapsible airways and lung
Keywords :
lung; muscle; physiological models; pneumodynamics; viscoelasticity; Campbell diagram; Lagrangian analysis; collapsible airways; compliant compartment; elastic work; forced vital capacity manoeuvres; lung tissue; muscular effort; nonlinear model; panting; partitioning; pleural pressure; pulmonary function laboratory test; respiratory mechanics; respiratory muscles; tidal breathing; viscous resistance; work of breathing; Biomedical computing; Biomedical engineering; Chemical engineering; Information analysis; Laboratories; Lungs; Mathematical model; Respiratory system; Surges; Testing;
Conference_Titel :
Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
Print_ISBN :
0-7803-4262-3
DOI :
10.1109/IEMBS.1997.758783
