DocumentCode
3372390
Title
Hydrolyticmicroneedles as Transdermal Drug Delivery System
Author
Miyano, T. ; Miyachi, T. ; Okanishi, T. ; Todo, H. ; Sugibayashi, K. ; Uemura, T. ; Takano, N. ; Konishi, S.
Author_Institution
Ritsumeikan Univ., Kusastu
fYear
2007
fDate
10-14 June 2007
Firstpage
355
Lastpage
358
Abstract
We developed hydrolytic microneedles as a transdermal drug delivery system to overcome the shortcomings of existing microneedle-systems: long-term stay of broken needles in the skin and high cost for safe disposal of used needles. The present microneedles spontaneously dissolve by hydrolysis in human skin as well as in the (boiled) water. We verified their basic utility through experiments.
Keywords
bioMEMS; biomedical equipment; drug delivery systems; needles; skin; MEMS; human skin; hydrolytic microneedles; microfabrication; transdermal drug delivery system; Costs; Drug delivery; Epidermis; Fabrication; Humans; Mice; Needles; Pharmaceutical technology; Sensor arrays; Skin; Bio-degradable; Drug delivery system; Hydrolytic; Microneedle;
fLanguage
English
Publisher
ieee
Conference_Titel
Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International
Conference_Location
Lyon
Print_ISBN
1-4244-0842-3
Electronic_ISBN
1-4244-0842-3
Type
conf
DOI
10.1109/SENSOR.2007.4300141
Filename
4300141
Link To Document