Title :
Phototransistor-Based Optoelectronic Tweezers for Cell Manipulation in Highly Conductive Solution
Author :
Hsu, H.Y. ; Ohta, A.T. ; Chiou, P.Y. ; Jamshidi, A. ; Wu, M.C.
Author_Institution :
Berkeley Sensor & Actuator Center, Berkeley
Abstract :
We report on a novel phototransistor-based optoelectronic tweezers (OET) that, for the first time, enables operation in high-conductivity solutions, such as physiological buffers and cell culture media. This new capability allows the manipulation of cells in biocompatible environments. The controlled transport of HeLa and Jurkat cells at velocities of up to 35 mum/s in phosphate-buffered saline (PBS) solution has been demonstrated.
Keywords :
biomedical engineering; cellular biophysics; optoelectronic devices; phototransistors; HeLa cells; Jurkat cells; cell culture media; cell manipulation; highly conductive solution; phosphate-buffered saline solution; phototransistor-based optoelectronic tweezers; physiological buffers; Actuators; Biomedical optical imaging; Cells (biology); Dielectrophoresis; Impedance; Optical buffering; Optical control; Optical sensors; Photoconducting devices; Photoconductivity; Optoelectronic tweezers; cell manipulation; dielectrophoresis;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International
Conference_Location :
Lyon
Print_ISBN :
1-4244-0842-3
Electronic_ISBN :
1-4244-0842-3
DOI :
10.1109/SENSOR.2007.4300171
