Quantification of asynchronous displacement of heart borders

An improved model is developed for studying frame-by-frame segmental wall motion based on the centerline method. The method measures motion along perpendiculars to a centerline drawn midway between the end diastolic and end systolic contours. However, when motion is `asynchronous´, wall motion may appear akinetic or dyskinetic, and the perpendiculars defined at the end systole may intersect each other at other time points in the cardiac cycle. A solution is presented that is based on constructing a centerline between two borders representing the locus of maximum motion of each heart