Simultaneous Dielectrophoretic Separation and Impedimetric Detection of Microbeads using Interdigitated Electrodes Array

Author

Zou, Zhiwei ; Lee, Soo-Hyun ; Ahn, Chong H.

Author_Institution

Univ. of Cincinnati, Cincinnati

fYear

2007

fDate

10-14 June 2007

Firstpage

1341

Lastpage

1344

Abstract

This paper presents a polymer microfluidic biochip integrated with interdigitated electrodes arrays (IDAs), which is used for simultaneous separation, accumulation, and detection of microbeads using dielectrophoresis (DEP) and electrical impedance spectroscopy (EIS) methods. The DEP response of silica microspheres has been characterized, and microspheres with different sizes (1.8 mum and 3.5 mum) have been successfully separated and individually trapped in different microchambers with IDAs. Simultaneously, the impedance variation caused by captured microspheres at IDAs has been analyzed.

Keywords

arrays; bioMEMS; biological techniques; electrochemical electrodes; electrochemical impedance spectroscopy; electrophoresis; lab-on-a-chip; microfluidics; particle size; polymers; silicon compounds; SiO₂; dielectrophoretic separation; electrical impedance spectroscopy methods; interdigitated electrodes array; microbeads accumulation; microbeads impedimetric detection; polymer microfluidic biochip; silica microspheres; size 1.8 mum; size 3.5 mum; Dielectrophoresis; Electrochemical impedance spectroscopy; Electrodes; Fabrication; Frequency; Immune system; Impedance measurement; Microfluidics; Polymers; Silicon compounds; Dielectrophoresis; Impedance Spectroscopy; Interdigitated Electrodes Arrays; Microbeads;

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International

Conference_Location

Lyon

Print_ISBN

1-4244-0842-3

Electronic_ISBN

1-4244-0842-3

Type

conf

DOI

10.1109/SENSOR.2007.4300390

Filename

4300390