Assessment of mean arterial blood pressure using spectral and chaotic analyses in different antihypertensive drug treatments

Mean arterial blood pressure (MBP) was anabzed by spectral and chaotic anabses in hypertensive patients. Two antihypertensive drugs, Cozaar and Renifec, were adopted to investigate the efects on U B P . 17 subjects were separated randomly into two groups. MBP was acquired during both supine and tilt-up positions before and after treatment. Correlation dimension (CO/ was applied to evaluate the complexify of MBP. In spectral analysis, the ratio of low- to high-frequency power was increased more in the group with Renitec. It may indicate that Cozaar has more manijesf effect for suppressing the activiv of sympathetic nervous system. In [he iwo groups. CD values of WBP increased in the supine position. The nonlinear analysis results might reveal that patients will tend to be noma1 with the two drugs. Keyword: mean arterial blood pressure (MBP), spectral analysis, chaos, correlation dimension (CO)