Title :
A High Throughput Microfluidic Bioparticle Sensor
Author :
Zhe, Jiang ; Jagtiani, Ashish ; Dutta, Prashanta ; Hu, Jun ; Carletta, Joan
Author_Institution :
Univ. of Akron, Akron
Abstract :
A micromachined resistive pulse sensor with multiple sensing microchannels was fabricated and tested. The device has multiple sensing channels operating in parallel, but integrated with just one sample reservoir and one power source. The throughput is improved significantly in comparison to a single channel device. The results with this four-channel device show that this device is capable of differentiating and counting micro polymethacrylate particles and Juniper pollens rapidly. A unique design, placing measurement microelectrodes in the center of the microchannels to circumvent the crosstalk caused by automatic electrical connection among microchannels is demonstrated.
Keywords :
biosensors; microelectrodes; microfluidics; Juniper pollens; automatic electrical connection; bioparticle sensor; micro polymethacrylate particles; microelectrodes; microfluidics; micromachined resistive pulse sensor; multiple sensing microchannels; Biosensors; Counting circuits; Crosstalk; Electrodes; Glass; Immune system; Microchannel; Microfluidics; Resistors; Throughput; Bioparticle sensor; High throughput; Micro Coulter counter; Multi-channel sensor;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International
Conference_Location :
Lyon
Print_ISBN :
1-4244-0842-3
Electronic_ISBN :
1-4244-0842-3
DOI :
10.1109/SENSOR.2007.4300510
