A High Throughput Microfluidic Bioparticle Sensor

Author

Zhe, Jiang ; Jagtiani, Ashish ; Dutta, Prashanta ; Hu, Jun ; Carletta, Joan

Author_Institution

Univ. of Akron, Akron

fYear

2007

fDate

10-14 June 2007

Firstpage

1825

Lastpage

1828

Abstract

A micromachined resistive pulse sensor with multiple sensing microchannels was fabricated and tested. The device has multiple sensing channels operating in parallel, but integrated with just one sample reservoir and one power source. The throughput is improved significantly in comparison to a single channel device. The results with this four-channel device show that this device is capable of differentiating and counting micro polymethacrylate particles and Juniper pollens rapidly. A unique design, placing measurement microelectrodes in the center of the microchannels to circumvent the crosstalk caused by automatic electrical connection among microchannels is demonstrated.

Keywords

biosensors; microelectrodes; microfluidics; Juniper pollens; automatic electrical connection; bioparticle sensor; micro polymethacrylate particles; microelectrodes; microfluidics; micromachined resistive pulse sensor; multiple sensing microchannels; Biosensors; Counting circuits; Crosstalk; Electrodes; Glass; Immune system; Microchannel; Microfluidics; Resistors; Throughput; Bioparticle sensor; High throughput; Micro Coulter counter; Multi-channel sensor;

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International

Conference_Location

Lyon

Print_ISBN

1-4244-0842-3

Electronic_ISBN

1-4244-0842-3

Type

conf

DOI

10.1109/SENSOR.2007.4300510

Filename

4300510