Micro-Dissecting Dual-Probe Testicular Tubule Assay

Author

Ramkumar, A. ; Chen, X. ; Paduch, D.A. ; Schlegel, P.N. ; Lai, Andy

Author_Institution

Cornell Univ., Ithaca

fYear

2007

fDate

10-14 June 2007

Firstpage

1959

Lastpage

1962

Abstract

We report on a microfabricated silicon probe integrated with an ultrasonic actuator and polysilicon strain gauges for Microdissection TEsticular Sperm Extraction (TESE) surgery. Insertion experiment was performed on rat testis tissue and by sensing the strain we were able to ascertain the size of the sperm-carrying microtubules in the sample. This information is important in Microdissection TESE to distinguish tubules with and without fertile sperm, eliminating large incision currently required for optical spermatazoa localization. Experimental data on tissue rigidity measurements indicate that the micromechanical assay can also be used for minimally-invasive testicular cancer detection.

Keywords

bioMEMS; biological techniques; biological tissues; biosensors; cancer; strain gauges; TESE; dual-probe testicular tubule assay; microdissection testicular sperm extraction; optical spermatazoa localization; polysilicon strain gauges; rat testis tissue; testicular cancer detection; tissue rigidity measurement; ultrasonic actuator; Actuators; Biomedical optical imaging; Capacitive sensors; Data mining; Optical sensors; Performance evaluation; Probes; Silicon; Surgery; Testing; micro-probe; seminiferous tubules; strain gauge; testicle;

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International

Conference_Location

Lyon

Print_ISBN

1-4244-0842-3

Electronic_ISBN

1-4244-0842-3

Type

conf

DOI

10.1109/SENSOR.2007.4300544

Filename

4300544