Title :
Portable biomarker detection with magnetic nanotags
Author :
Hall, Drew A. ; Wang, Shan X. ; Murmann, Boris ; Gaster, Richard S.
Author_Institution :
Dept. of Electr. Eng., Stanford Univ., Stanford, CA, USA
fDate :
May 30 2010-June 2 2010
Abstract :
This paper presents a hand-held, portable biosensor platform for quantitative biomarker measurement. By combining magnetic nanoparticle (MNP) tags with giant magnetoresistive (GMR) spin-valve sensors, the hand-held platform achieves highly sensitive (picomolar) and specific biomarker detection in less than 20 minutes. The rapid analysis and potential low cost make this technology ideal for point-of-care (POC) diagnostics. Furthermore, this platform is able to detect multiple biomarkers simultaneously in a single assay, creating a promising diagnostic tool for a vast number of applications.
Keywords :
biosensors; giant magnetoresistance; microprocessor chips; nanoelectronics; nanoparticles; giant magnetoresistive spin valve sensor; hand held biosensor; magnetic nanoparticle tag; multiple portable biomarker detection; point-of-care diagnostic; portable biosensor; quantitative biomarker measurement; Biomarkers; Biosensors; Costs; Fluorescence; Giant magnetoresistance; Immune system; Light emitting diodes; Magnetic analysis; Magnetic sensors; Personal digital assistants;
Conference_Titel :
Circuits and Systems (ISCAS), Proceedings of 2010 IEEE International Symposium on
Conference_Location :
Paris
Print_ISBN :
978-1-4244-5308-5
Electronic_ISBN :
978-1-4244-5309-2
DOI :
10.1109/ISCAS.2010.5537639
