• DocumentCode
    3397949
  • Title

    A novel parallel motif discovery algorithm based on de Bruijn graph

  • Author

    Zhou, Hong ; Zhao, Zheng ; Wang, Hongpo

  • Author_Institution
    Sch. of Comput. Sci. & Technol., Tianjin Univ., Tianjin, China
  • Volume
    2
  • fYear
    2010
  • fDate
    30-31 May 2010
  • Firstpage
    139
  • Lastpage
    142
  • Abstract
    this paper attempts to provide a new approach to discover conserved regions such as motifs in either DNA or Protein sequences. We not only use the idea of de Bruijn graphs, but also follow a parallel approach to solve this problem. The de Bruijn graph has been successfully adopted to solve problems such as local alignment and DNA fragment assembly. To accelerate the speed, our method harnesses the power of parallelism to discover the conserved regions in a DNA or protein sequence. We have found that the algorithm was successful in mining signals for larger number of sequences and at a faster rate when compared to some popular motif searching tools.
  • Keywords
    Agricultural engineering; Assembly; Automation; Computer science; DNA; Diseases; Evolution (biology); Mechatronics; Parallel processing; Protein sequence; Motif; de bruijn graph; parallel;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Industrial Mechatronics and Automation (ICIMA), 2010 2nd International Conference on
  • Conference_Location
    Wuhan, China
  • Print_ISBN
    978-1-4244-7653-4
  • Type

    conf

  • DOI
    10.1109/ICINDMA.2010.5538350
  • Filename
    5538350