DocumentCode
3397949
Title
A novel parallel motif discovery algorithm based on de Bruijn graph
Author
Zhou, Hong ; Zhao, Zheng ; Wang, Hongpo
Author_Institution
Sch. of Comput. Sci. & Technol., Tianjin Univ., Tianjin, China
Volume
2
fYear
2010
fDate
30-31 May 2010
Firstpage
139
Lastpage
142
Abstract
this paper attempts to provide a new approach to discover conserved regions such as motifs in either DNA or Protein sequences. We not only use the idea of de Bruijn graphs, but also follow a parallel approach to solve this problem. The de Bruijn graph has been successfully adopted to solve problems such as local alignment and DNA fragment assembly. To accelerate the speed, our method harnesses the power of parallelism to discover the conserved regions in a DNA or protein sequence. We have found that the algorithm was successful in mining signals for larger number of sequences and at a faster rate when compared to some popular motif searching tools.
Keywords
Agricultural engineering; Assembly; Automation; Computer science; DNA; Diseases; Evolution (biology); Mechatronics; Parallel processing; Protein sequence; Motif; de bruijn graph; parallel;
fLanguage
English
Publisher
ieee
Conference_Titel
Industrial Mechatronics and Automation (ICIMA), 2010 2nd International Conference on
Conference_Location
Wuhan, China
Print_ISBN
978-1-4244-7653-4
Type
conf
DOI
10.1109/ICINDMA.2010.5538350
Filename
5538350
Link To Document