• DocumentCode
    3403353
  • Title

    A novel discretization method for processing digital gene expression profiles

  • Author

    Jibin Qu ; Jinxia Zhang ; Chenyang Huang ; Baogui Xie ; Yong Wang ; Xiang-Sun Zhang

  • Author_Institution
    Inst. of Agric. Resources & Regional Planning, Chinese Acad. of Agric. Sci., Beijing, China
  • fYear
    2013
  • fDate
    23-25 Aug. 2013
  • Firstpage
    134
  • Lastpage
    138
  • Abstract
    Discretization serves as an important preprocessing step for analyzing gene expression data and many algorithms have been proposed. However, most of the discretization methods were designed for microarrays. As a new technology, digital gene expression (DGE) profiles can overcome the limitation of microarrays and were applied in a widely range. In this paper, we proposed a novel discretization method for DGE data and the validations in a time-series gene expression dataset proved the efficiency of our method.
  • Keywords
    RNA; data analysis; genetics; molecular biophysics; molecular configurations; time series; RNA sequences; digital gene expression profile processing; gene expression data analysis; microarrays; novel discretization method; time-series gene expression dataset; Bioinformatics; Fitting; Genomics; Indexes;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Systems Biology (ISB), 2013 7th International Conference on
  • Conference_Location
    Huangshan
  • ISSN
    2325-0704
  • Type

    conf

  • DOI
    10.1109/ISB.2013.6623808
  • Filename
    6623808