Delivery of inhaled nitric oxide from a 10% source by gas phase titration

Author

Gomez, Michael R. ; Moon, Jon K. ; Moreno, Juan A.

Author_Institution

Dept. of Pediatrics, Baylor Coll. of Med., Houston, TX, USA

Volume

2

fYear

1995

fDate

20-23 Sep 1995

Firstpage

1675

Abstract

A low-deadspace system was built to deliver inhaled nitric oxide (NO) from a concentrated (10%) source that reduces dilution of inhaled oxygen concentrations. NO was delivered to a target dosage over the range of 60 to 180 PPM. Inhaled oxygen concentration remained above 99% over the full NO range. Less than 3 PPM of NO₂, was produced at the maximum 180 PPM dose of NO. Only with this system can the efficacy of inhaled NO be tested as an adjunct to optimal conventional medical therapy. Future studies will investigate the true NO dose/response relationship

Keywords

biomedical equipment; lung; nitrogen compounds; patient treatment; 10% source; NO; NO dose/response relationship; NO₂; O₂; gas phase titration; inhaled nitric oxide delivery; inhaled oxygen concentration; low-deadspace system; medical instrumentation; medical therapy adjunct; optimal conventional medical therapy; target dosage; Arteries; Blood flow; Circuits; Condition monitoring; Diseases; Equations; Lungs; Oxygen; Pediatrics; System testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference

Conference_Location

Montreal, Que.

Print_ISBN

0-7803-2475-7

Type

conf

DOI

10.1109/IEMBS.1995.579886

Filename

579886