Oxygen measurement during limb blood flow restriction in primates

Noninvasive clinical assessment of limb oxygen is examined for tcpO₂ and differential light reflectance spectrography measurements during flow restriction in the limb. The comparisons are made using the compartment representation of oximetric responses. The study included femoral/iliac occlusion in the canine and limb tourniquet studies in primates. Laser Doppler was also recorded but did not correlate with the oxygen responses. Results from canines were variable presumably due to only partial occlusion of flow and the extensive collateral circulation present in the canine limb. The tcpO₂ data (partial pressure response) showed less variation among subjects than the reflectance data (saturation response). The difference is attributed to differences between oxygen partial pressure responses and oxygen saturation responses. The reflectance method was easier to use